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Hirokazu Tamamura Selected Research

HIV Fusion Inhibitors

1/2007Therapeutic potential of the chemokine receptor CXCR4 antagonists as multifunctional agents.
1/2007Development of low molecular weight CXCR4 antagonists by exploratory structural tuning of cyclic tetra- and pentapeptide-scaffolds towards the treatment of HIV infection, cancer metastasis and rheumatoid arthritis.
7/2004Identification of a CXCR4 antagonist, a T140 analog, as an anti-rheumatoid arthritis agent.

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Hirokazu Tamamura Research Topics

Disease

23Neoplasms (Cancer)
10/2021 - 08/2003
19Infections
01/2021 - 03/2002
9Neoplasm Metastasis (Metastasis)
10/2008 - 07/2002
8HIV Infections (HIV Infection)
12/2019 - 12/2005
8Acquired Immunodeficiency Syndrome (AIDS)
01/2019 - 02/2003
7Rheumatoid Arthritis
01/2019 - 07/2004
5Alzheimer Disease (Alzheimer's Disease)
10/2021 - 01/2011
4Carcinoma (Carcinomatosis)
01/2018 - 07/2002
3Leukemia
01/2019 - 09/2005
3Breast Neoplasms (Breast Cancer)
10/2008 - 08/2003
2Experimental Arthritis
10/2008 - 07/2004
2Melanoma (Melanoma, Malignant)
10/2008 - 12/2005
2Hypersensitivity (Allergy)
10/2008 - 07/2004
2Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia)
01/2007 - 01/2007
2Pancreatic Neoplasms (Pancreatic Cancer)
12/2005 - 01/2004
1Persistent Infection
01/2019
1Lung Injury
07/2011
1Arthritis (Polyarthritis)
10/2008
1Glioma (Gliomas)
03/2008
1Small Cell Lung Carcinoma (Small Cell Lung Cancer)
12/2005
1B-Cell Chronic Lymphocytic Leukemia (Chronic Lymphocytic Leukemia)
09/2005
1Lymphoma (Lymphomas)
02/2005

Drug/Important Bio-Agent (IBA)

11Chemokine ReceptorsIBA
01/2019 - 03/2002
11Peptides (Polypeptides)IBA
01/2018 - 03/2002
11T140 peptideIBA
01/2009 - 03/2002
5Protein Kinase CIBA
10/2021 - 01/2011
4Pharmaceutical PreparationsIBA
01/2019 - 02/2003
4Anti-HIV Agents (AIDS Drugs)IBA
10/2013 - 06/2004
4LigandsIBA
09/2008 - 08/2003
3CXCR4 Receptors (CXCR4 Receptor)IBA
07/2011 - 07/2004
34-fluorobenzoyl-TN-14003IBA
10/2008 - 08/2003
3HIV Fusion InhibitorsIBA
01/2007 - 07/2004
2Peptide Hydrolases (Proteases)FDA Link
01/2019 - 01/2018
2AntigensIBA
11/2016 - 04/2010
2Neutralizing AntibodiesIBA
04/2016 - 08/2003
2ChemokinesIBA
05/2006 - 02/2003
2G-Protein-Coupled Receptors (Receptors, G Protein Coupled)IBA
11/2003 - 07/2002
1AntibodiesIBA
01/2021
1Antiviral Agents (Antivirals)IBA
01/2021
1Therapeutic UsesIBA
01/2021
1Single-Chain AntibodiesIBA
12/2019
1EpitopesIBA
12/2019
1IntegrasesIBA
01/2019
1RNA-Directed DNA Polymerase (Reverse Transcriptase)IBA
01/2019
1KLA peptideIBA
01/2018
1Cyclic PeptidesIBA
01/2018
1ErbB Receptors (EGF Receptor)IBA
01/2018
1Immunoglobulins (Immunoglobulin)IBA
12/2013
1YYA-021IBA
12/2013
1Viral RNAIBA
12/2013
1CCR5 Receptors (CCR5 Receptor)IBA
11/2013
1Viral ProteinsIBA
11/2013
1Human immunodeficiency virus 1 p31 integrase proteinIBA
10/2013
1EnzymesIBA
10/2013
1Viral DNAIBA
10/2013
1Reverse Transcriptase InhibitorsIBA
01/2012
1HIV Protease InhibitorsIBA
01/2012
1LipopolysaccharidesIBA
07/2011
1EndotoxinsIBA
07/2011
14- fluorobenzoyl- Arg- Arg- Nal- Cys- Tyr- Cit- Lys- Lys- Pro- Tyr- Arg- Cit- Cys- Arg- NH2 (S-S bridged)IBA
01/2009
1aplavirocIBA
06/2008
1111indium-DTPA-Ac-TZ14011IBA
05/2006
1RadiopharmaceuticalsIBA
05/2006
1CalciumIBA
03/2006
1Glycoproteins (Glycoprotein)IBA
03/2006
1KisspeptinsIBA
01/2006
1Chemokine CXCL12IBA
12/2005
1Nelfinavir (Viracept)FDA Link
06/2004
1Protease Inhibitors (Protease Inhibitor)IBA
06/2004
1Laminin (Merosin)IBA
01/2004
1TN14003IBA
01/2004
1Mitogen-Activated Protein KinasesIBA
01/2004
1TC14012IBA
02/2003
1AcidsIBA
05/2002

Therapy/Procedure

4Therapeutics
01/2021 - 08/2003
4Drug Therapy (Chemotherapy)
10/2008 - 06/2004
2Highly Active Antiretroviral Therapy (HAART)
01/2019 - 01/2012
2Subcutaneous Injections
07/2004 - 08/2003
1Intraperitoneal Injections
02/2005